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Delta Gap & Delta Ratio Calculator

Δ-gap = AG − 12; Δ-ratio = (AG − 12) / (24 − HCO₃).

Compute the delta gap and delta ratio from the anion gap and serum bicarbonate to detect mixed acid-base disorders. Δ-ratio < 1 suggests a coexisting non-anion-gap acidosis; > 2 suggests a concomitant metabolic alkalosis.

Published Last reviewed 1 min read

Inputs

mEq/L
mEq/L

Results

Enter values and click Calculate to see results.
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How to use this calculator

  1. Fill in the inputs above using the units you already have.
  2. Values update automatically as you type — no submit button needed.
  3. Hover any result row for the underlying formula and intermediate values.

Formula

Δ-gap = AG − 12; Δ-ratio = (AG − 12) / (24 − HCO₃).

In depth

Compute the delta gap and delta ratio from the anion gap and serum bicarbonate to detect mixed acid-base disorders. Δ-ratio < 1 suggests a coexisting non-anion-gap acidosis; > 2 suggests a concomitant metabolic alkalosis.