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Mutation-Selection Balance Calculator

Equilibrium allele frequency q̂ = √(μ / s).

Compute the equilibrium frequency of a deleterious recessive allele under mutation-selection balance for a randomly mating diploid population: q̂ = √(μ / s) for a recessive allele, or q̂ ≈ μ / (h·s) for a partially dominant one.

Priya Venkatesan By Priya Venkatesan
Published Last reviewed 1 min read

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How to use this calculator

  1. Fill in the inputs above using the units you already have.
  2. Values update automatically as you type — no submit button needed.
  3. Hover any result row for the underlying formula and intermediate values.

Formula

Recessive: q̂ = √(μ / s). Partially dominant: q̂ ≈ μ / (h · s).

In depth

Compute the equilibrium frequency of a deleterious recessive allele under mutation-selection balance for a randomly mating diploid population: q̂ = √(μ / s) for a recessive allele, or q̂ ≈ μ / (h·s) for a partially dominant one.