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Time to Steady State Calculator

~5 half-lives to reach ≥ 96.9% of steady state.

Estimate the time required for repeated dosing to reach steady-state plasma concentrations from the drug elimination half-life. Reports time to reach 50%, 90%, 95%, and 99% of steady state.

Priya Venkatesan By Priya Venkatesan
Reviewed by Dr. Helena Ortiz
Published Last reviewed 1 min read

Inputs

h

Results

Enter values and click Calculate to see results.
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How to use this calculator

  1. Fill in the inputs above using the units you already have.
  2. Values update automatically as you type — no submit button needed.
  3. Hover any result row for the underlying formula and intermediate values.

Formula

Css fraction = 1 − (½)^(t / t½). Inverse: t = t½ · log₂(1 / (1 − f)).

In depth

Estimate the time required for repeated dosing to reach steady-state plasma concentrations from the drug elimination half-life. Reports time to reach 50%, 90%, 95%, and 99% of steady state.